Dr. John Wyrick is a professor in the School of Molecular Biosciences, where he studies mechanisms of DNA damage, repair, and mutagenesis in a variety of model organisms, including yeast and human cells. His lab has developed and used high-throughput sequencing approaches to map DNA damage and repair across the genome at single nucleotide resolution. Dr. Wyrick currently teaches a course on bioinformatics.
Education
- PhD, Massachusetts Institute of Technology, 2002
- BS, Washington State University, 1996
Research Interest
- Mechanisms of mutagenesis by ultraviolet (UV) light in skin cancer
- Repair of UV damage by nucleotide excision repair (NER)
- Modulation of UV damage formation by chromatin and transcription factor proteins
- Regulation of gene expression by transcription factor binding sites