- Associate Professor
Biography
- Director, Gene Editing Reagent Core
Throughout my research career I have developed and used animal models to study different aspects of biology and disease. This includes generating transgenic and conditional knockout mouse lines, and numerous zebrafish lines including those gene edited through CRISPR and TALEN, mutated with retrovirus, as well as transgenic animals. As the director of the Gene Editing Reagent Core (GERC) and part of the Functional Genomics Initiative (FGI) at Washington State University, I’m using my experience in these areas to generate new models and approaches for gene editing for investigators who are using a variety of model systems. The GERC has provided multiple labs with DNA constructs for CRISPR editing as well as constructs for other use including virus production. In conjunction with the Animal Production Core (APC), we have produced many mouse lines including CRISPR knockouts, a deletion of a 27 kb segment containing multiple closely related genes, knock-in mice adding a short epitope tag sequence onto the endogenous gene, and knock-in mice with large sequence insertions.
Education
- PhD, Baylor College of Medicine, 2003
- BS University of Puget Sound, 1992