School of Molecular Biosciences

Gene-edited livestock ‘surrogate sires’ successfully made fertile

For the first time, a team of scientists led by WSU’s Jon Oatley have created pigs, goats and cattle that can serve as viable “surrogate sires,” male animals that produce sperm carrying only the genetic traits of donor animals.

One of the "surrogate sire" goats on the WSU Pullman campus, photographed in August 2020.

5 Questions with School of Molecular Biosciences alumna Jennifer Adair

Jennifer Adair (’05 PhD, School of Molecular Biosciences) had never heard of Pullman when she considered WSU’s National Institute of Health Protein Biotechnology Training Program. She even shamefully admits, at first, she confused WSU with the University of Washington. Now, the Coug is developing gene therapies to treat genetic disorders, HIV and cancer. Adair is a faculty member in the Clinical Research Division at the Fred Hutchinson Cancer Research Center in Seattle. Her goal: provide safe, cost-effective applications for gene therapy that can be implemented worldwide.

Jennifer Adair in her lab at the Fred Hutchinson Cancer Research Center in Seattle.

Understanding immunity to improve health

Just a few short hours after illness-causing bacteria enter the human body, a sophisticated defense system goes to work. The immune system quickly recognizes the foreign invaders and sends a well-orchestrated, frontline defense.

“Innate immunity is ancient,” says Alan Goodman, assistant professor in the School of Molecular Biosciences and affiliate faculty in the Paul G. Allen School for Global Animal Health. “Our bodies have many ways of fighting infectious disease, but innate immunity is something that must be important for it to have persisted.”

Dr. Goodman and Marena Guzman in Dr. Goodman's laboratory.